GHB
THE FACTS
Gamma hydroxybutyrate (GHB) is an illicit
chemical that has become a major cause of
drug-related comas in the US and other countries. In
fact, the number of GHB overdoses in the United
States has now out-paced overdoses from MDMA
(Ecstasy). GHB was rejected by the American medical
community in the 1960s, but has become popular among
many people for its ability to cross the blood-brain
barrier freely and depress consciousness, resulting
in euphoria and intoxication. It is also touted on
the Internet as a sleep aid, an anti-depressant and
weight loss product, although these uses are not
substantiated by reality and may carry a potentially
deadly twist. Starting first as an alternative to
steroids in the late 1980s, when steroids were being
controlled, GHB has grown into a multi-headed
medical nightmare, draining emergency room services,
shattering the lives of those who have lost loved
ones to it, and terrifying families/friends of those
addicted to it. Yet it is still a mystery to most
law enforcement officers, medical/coroner personnel,
and parents.
GHB was first
synthesized in France more than 40 years ago as a
possible anesthetic, but because of its undesirable
side effects was rejected by the American medical
community. Its legal use anywhere is dwindling as
countries are beginning to recognize the problems.
GHB resurfaced in 1987 as an orphan drug being
researched to treat the combination of sleep
disorders known as narcolepsy/cataplexy. At about
the same time, steroid users were told that it might
enhance the body’s production of growth hormone
(in deep sleep state). However, due to growing
numbers of overdoses, it was ordered off the shelves
of stores in November 1990. Unfortunately, it has
gained status as a recreational drug and as a rape
drug, and has become dangerously common. As a result
of increased restrictions on GHB itself, its “analogs,”
or chemical cousins that turn into GHB in the body,
have become increasingly prevalent.
WHAT IS GHB
GHB (Gamma hydroxybutyrate) usually comes as an
odorless liquid, slightly salty to the taste, and
sold in small bottles. It has also been found in
powder and capsule form.
It is classified as a sedative-hypnotic, and was
originally developed as a sleep-aid.
GHB (gamma-hydroxybutyrate) has been abused in
the U.S. for euphoric, sedative, and anabolic
(body-building) effects. GHB use associated with
sexual assault.
THE EFFECTS OF GHB
Lower doses of GHB have a euphoric effect similar
to alcohol and can make the user feel relaxed, happy
and sociable. Higher doses can make the user feel
dizzy and sleepy and can sometimes cause vomiting,
muscle spasms and loss of consciousness. Overdoses
will always cause loss of consciousness (temporary
coma) and will slow down breathing. Sometimes, and
particularly if mixed with alcohol, GHB can slow
breathing down to a dangerously low rate, which has
caused a number of deaths. Coma and seizures can
occur following abuse of GHB and, when combined with
methamphetamine, there appears to be an increased
risk of seizure. Combining use with other drugs such
as alcohol can result in nausea and difficulty
breathing. GHB may also produce withdrawal effects,
including insomnia, anxiety, tremors, and sweating.
Repeated use can lead to addiction and tough
withdrawal.
GHB’s depressant
effects on the brain in low doses produce a high or
euphoric feeling as inhibitions are depressed. When
the dose is increased, profound coma results. The
heart rate may also be depressed or slowed. Effects
on the nervous system may result in a spasm of
muscle contractions called myoclonus, producing
seizure-like movements. Other effects such as
confusion, amnesia, vomiting and irregular breathing
are dangerous when combined with the major
depressant effects of GHB. Other drugs in
combination with GHB, especially other depressants
such as alcohol, may worsen the depressive effects
and increase the possibility of a fatal outcome. The
“desired” effects for GHB in low doses may sound
inviting, but the consequence of the wrong dose may
be death. The dosage response of GHB is quite steep,
meaning that a tiny increase in dose may cause a
dramatic increase in symptoms and, thus, in risk.
Variable effects mean that a teaspoon might be
perfect one time, but may become an overdose the
next time! It is also important to be aware of the
consequences that occur when GHB is mixed with other
chemicals. For instance, mixing GHB with alcohol or
other depressants is even more likely to result in
death. The effects last about four hours and can
resolve quite suddenly.
STREET NAMES
GHB’s street names include "G,"
Liquid Ecstasy, Georgia Home Boy, Grievous Bodily
Harm, Gamma G, Somatomax, Growth Hormone
Booster,Soap and Easy Lay.
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